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Applications using Fresh Frozen Human Tissues

Human Biospecimens for Research

Unlocking the full potential of human biospecimens is vital for driving ground-breaking scientific research. Discover the disease state tissues, biological specimens, and applications that can empower your research and make a lasting impact on human health and disease.

Blood samples are often used to diagnose AML, monitor disease progression, and evaluate response to treatment. Researchers can analyze the blood cells and their genetic mutations to identify potential targets for therapy.

Bone marrow is the spongy tissue inside bones where blood cells are produced. Bone marrow biopsies and aspirates are commonly used to diagnose AML and determine the extent of the disease. Bone marrow samples are also used to study the disease’s molecular and genetic characteristics.

Tissue samples from the spleen, lymph nodes, or other affected organs can provide valuable information on the extent and progression of AML and potential therapy targets.

Researchers can create cell lines from AML samples to study the disease in a controlled laboratory environment. These cell lines can be used to test potential treatments and identify new therapeutic targets.

Researchers can isolate DNA and RNA from AML samples to study the genetic mutations and gene expression patterns associated with the disease. This information can be used to identify potential targets for therapy and develop new diagnostic tools.

Human Biospecimens for Acute Myeloid Leukaemia Research

Elucidating Molecular and Genetic Characteristics

The main challenges in developing qRT-PCR assays for cancer screening are identifying suitable biomarkers, designing specific and efficient primers and probes, optimising assay parameters, and validating the assay using human biospecimens. Validate the assay using diverse specimens, such as blood, saliva, or tissue biopsies, to confirm its performance in detecting the target biomarker in the intended patient population.

Cancer Research Methodology for Novel qRT-PCR Assays

To Detect and Quantify Gene Expression and Mutations

The use of human biospecimens for research has significant potential to contribute to the achievement of the United Nations' SDGs, ultimately promoting sustainable development and improving the quality of life for people worldwide.

Human Biospecimens for Research into the United Nations SDGs

Biospecimens Play a Crucial Role in Sustainable Development Goals

Chronic lymphocytic leukaemia (CLL) is a type of blood cancer characterized by the uncontrolled proliferation of mature B-lymphocytes. Research in CLL aims to better understand its pathophysiology, identify novel therapeutic targets, and improve patient outcomes. Human biospecimens, including blood, bone marrow, and lymph node tissues, play an essential role in CLL research. This white paper explores the importance of these specimens, the ethical considerations for their collection, and their role in advancing the understanding and treatment of CLL.

Human Biospecimens for Chronic Lymphocytic Leukaemia Research

Exploring their importance and ethical considerations of collection

Human biospecimens serve as invaluable resources in neuroscience research, aiding our understanding of the brain's complex mechanisms and developing novel diagnostic and therapeutic strategies. This article will discuss the best clinical specimens for neuroscience research, including cerebrospinal fluid, blood, brain tissue, saliva, and skin biopsies, while emphasizing the importance of the appropriate collection, storage, and handling procedures to maximize scientific outcomes.

Human Biospecimens for Neuroscience Research

Choice Depends on the Research Question and the Accessibility of the Specimen Type

Human biospecimens for cancer research are biological samples that are collected from patients who have been diagnosed with cancer. These biosamples can be collected from various parts of the body, including the tumour itself, adjacent normal tissue, and biofluids like blood or urine.

Human Biosamples for Cancer Research

Research Applications for these Essential Tools in Oncology Research

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